Module 4: Evidence for Natural Selection

These free OCR A Level Biology Evidence for Natural Selection revision notes have been written for specification points 4.2.2(e) and 4.2.2(i).

Evidence for Natural Selection and Evolution

Anatomy, DNA, fossils, biomolecules and real-time observations provide evidence and examples for species evolving by natural selection.


Fossil Evidence

Fossils are the preserved remains or traces of organisms from the past. 

The fossil record provides direct evidence of:

  • Extinct species that once existed
  • New species which resemble older ones
  • Transitional fossils which show intermediate changes

Anatomical Evidence

Similarities and differences in the anatomical structures of different species offer insight into evolutionary relationships.

Homologous structures are anatomical features which are present in different species, but have adapted over time to serve different functions, such as the bones found in a human hand vs the same bones found in a bat’s wing.


Genetic Evidence for Evolution

The discovery of DNA and the development of techniques to sequence and compare different genes and genomes allow for evolutionary changes and relationships to be accurately explored.

The table below outlines some of the different types of genetic material that can be investigated:

EvidenceWhat It Shows
DNA sequence similarityClosely related species have more similar base (DNA) sequences.
% of shared genes/conserved genesHomologous (matching) genes appear in many species, indicating descent from a common ancestor and the genes’ importance in being selected for.
Genetic markers/mutationsShared mutations or marker sequences indicate common ancestry.
Biomolecular Evidence

The biomolecules synthesised in organisms are determined by their underlying genetic code. In some situations it may be easier, or more informative, to examine and compare these, particularly proteins, to determine evolutionary relationships.

The table below outlines the different biomolecules which can be investigated:

EvidenceWhat It Shows
Shared amino acid sequences in proteinsClosely related species have similar or identical amino acid sequences.
Differences in protein primary structureDistantly related species have more differences.
Shared non-coding DNAIdentical sequence insertions passed down from a common ancestor.
Mutated DNA repeat regionsSome mutations have harmful effects, but may still be passed on.
Observing Evolution Today

While most evolutionary changes take place over long periods, some examples of natural selection can be seen happening within just a few generations. These examples often arise in response to strong selection pressures such as drugs, pollution, or pesticides.

They demonstrate how beneficial traits can become more common over time.

The table below outlines some important examples of modern evolution in action:

ExampleWhat It Shows
Antibiotic resistanceRandom mutations made some bacteria resistant, and these resistant strains became more common.
Peppered mothsChanges in pollution affected camouflage success, so darker or lighter morphs were selected.
Mosquitoes and DDTInsecticide use favoured resistant mosquitoes, so the population became resistant over time.
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.